摘要
用血小板自动平衡聚集仪建立血小板活化因子（ＰＭ）的生物活性检测法，检测了３１例各期矽肺患者（排除了肝硬化、肺心病）和２２例正常人血浆ＰＡＦ含量，结果表明矽肺患者ＰＡＦ含量（３．３７４５±０．６６１ｎｇ／ｍｌ）显著高于正常对照组人群（１．６９７６±０．５３４ｎｇ／ｍｌ），Ｐ＜０．０１，提示ＰＭ在矽肺病发生发展过程中可能具有重要的作用。
he plasma levels of platelet activating factor(PAF) were measured in 31 stages silicosis pa-tients and 22 controls, using platelet aggregation bioassay.The result showed that the levels of plasma PAF in silicosis patients were higher than thosein the controls(3. 3745±0. 661ng/ml:1. 6976±0. 534ng/ml P<0. 01).We conclude tht plasma PAF is increased in silicosis patients, and PAF could be involved inthe pathophysiological changes in silicosis.
出处
《职业卫生与病伤》
北大核心
1996年第4期198-199,共2页
Occupational Health and Damage
关键词
矽肺
血小板聚集
血小板活化因子
检测
platelet activating factor(PAF), silicosis, aggregation of blood platelet.
