摘要
为了研究肠易激综合征(IBS)患者直肠肛门运动功能,我们测定了50例IBS患者和11例正常人直肠肛门压力及排便功能,发现:(1)直肠静息压、肛门括约肌静息压及其最大缩窄压在IBS腹泻组、便秘组及正常对照组均无显著差异(P>0.05).(2)肛管高压带长度在IBS腹泻组及便秘组均显著高于正常对照组(P<0.0005).(3)直肠壶腹部的感觉阈值、最大耐受量等,在IBS腹泻组均显著低于正常对照组(P<0.005～0.0005).(4)IBS便秘组感觉阈值与正常对照组无差异(P>0.05),但其最大耐受量及引起直肠-肛门抑制反射的直肠扩张容量均显著高于正常对照组(P<0.05).提示IBS患者在静息状态下肛门括约肌的功能是正常的.但其排便功能和直肠感觉功能存在异常.
To study the rectoanal function in patients with irritable bowel syndrome (IBS), the rectoanal manometry were performed on 50 patients with diarrhea predominant type IBS (Dp-IBS), 20 patients with constipation predominant type IBS (Cp-IBS) and 11 normal subjects. The results showed: (1)The rectal resting pressure, the anal resting pressure and the maximum squeeze pressure of the anal sphincter were not different among the patients with Dp-IBS, Cp-IBS and normal subjects (P >0.05). (2)The length of high pressure zone in the patients with Dp-IBS and Cp-IBS were significantly higher than that in normal subjects (P<0. 0005). (3)The rectal sensitivity, maximum tolerance etc, in Dp-IBS were significantly lower than that in normal subjects (P < 0. 005 ~0. 0005). (4)The rectal sensitivity was not different between patients with Cp-IBS and normal subjects (P>0.05); The maximum tolerance and the rectal capacity causing rectoanal inhibitory reflex in patients with Cp-IBS were significantly higher than normal subjects (P<0.05). These results suggested: At resting state, the function of rectal and anal sphincter in patients with-IBS were normal, but its defecation function and rectal sensitivity were disordered.
出处
《临床消化病杂志》
1996年第4期156-158,共3页
Chinese Journal of Clinical Gastroenterology
