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生物碱类抗肿瘤药物及其新剂型的研究进展 被引量:9

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作者 张彦 陈燕忠
出处 《药品评价》 CAS 2006年第4期264-266,共3页 Drug Evaluation
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  • 1WALL M E, WANI M C, COOK C E, et al. Antitmnor agent I. The isolation and structure of Camptothecin, a novel alkaloidal leukemia and tumor inhibitor from camptotheca acuminata[J]. Amer Chem Soc1966,88(16) :3 888- 3 890.
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  • 3HSIANG Y H, HERTZRERG R, HECHT S, et al. Camptothecin induces protein- linked DNA breaks via man malian DNA topoisomerase I [J]. Biol Chem, 1985,260(27) : 14 873 - 14 878.
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  • 6CIUFOLINI M A. Practical Total Synthesis of ( + ) - Camptothecin: The Full Story[J]. Tetrahedmn, 1997,53(32) : 11 049.
  • 7CROW R T, CROTHERS D M. Structural modifications of camptothecin and effects on topoisomerase I inhibition [ J ]. Med Chem,1992,435(22) :4 160.
  • 8WALL M E, WANI M C. Camptothecin and taxol:discovery to clinic-thirteenth Bruce F. Cain memorial award lecture [ J ]. Cancer Res,1995,55( 1 - 3) :753 - 760.
  • 9LAVERGNE O, DEMARQUAY D, BAILLY C, et al. The novel silatecan 7- tert- butyl dimethylsilyl- 10- hydroxycamiptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity[J ]. Med Chem, 2000,43(11) :2 285 - 2 289.
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