摘要
目的探讨局部应用伯克纳(丙酸倍氯米松鼻气雾剂)治疗变应性鼻炎的临床效果。方法对96例变应性鼻炎患者,分两组,一组应用鼻腔内鼻喷雾剂伯克纳,每次每侧鼻孔内喷50ug,2个鼻孔共100ug;另一组口服抗组织胺药酮替芬,每次1mg,共治疗4周。做症状及体征分级记分及疗效评定。结果治疗后各项症状及体征评分均明显下降,治疗后与治疗前比较,症状及体征评分差异有统计学意义(P<0.05);总有效率为87.5%(伯克纳)、79.1%(酮替芬)。二者疗效比较无统计学意义(P>0.05)。结论伯克纳可有效控制与改善变应性鼻炎患者的临床症状。
Objective An open randomized comparative Study was conducted in order to observe the efficacy about intranasal Beconase in the treatment of allergic rhinitis. Hethod Forty-eight patients with allergic rhinitis were treated with Beconase aqueous nasal spray （100ug once daily intra-nasally ） for 4 weeks. Another forty-eight patients with allergic rhinitis take one pill of Ketotifen per day. Efficacy was evaluated by measurement of nasal symptom scores and sign scores. Result All the parameters measured were improved after treatment . the scores of nasal secretions ,itchy feeling of the nose showed a significant decrease than that before treatment（P〈0. 05 ）. No serious adverse events were reported in the study . Conclusion Intranasal Beconase was effective and safe in alleviating the symptoms of allergic rhinitis .
出处
《国际医药卫生导报》
2006年第18期60-61,共2页
International Medicine and Health Guidance News
