摘要
目的制备冻形更好的注射用奥沙利铂,并考察其质量。方法用甘露醇(作为赋形剂)与主药奥沙利铂制成冻干无菌粉针,并依照注射用奥沙利铂的国家质量标准进行质量考察。结果与结论制备工艺比较简单,制成的注射用奥沙利铂无菌冻干品成形好,不易碎,质量符合国家标准。
Objective To found simple preparing technique and better lyophillization form of oxaliplatin for injection. Methods Sterile injection powder was prepared with MNT as excipient and oxaliplatin as principal agent, and the quality was investigated according to official quality criteria of oxaliplatin for injection. Results and Conclusion The preparing technique of oxaliplatin for injection is simple using the prescription, and lyophillization form of oxaliplatin for injection is good. The sterile injection powder of oxaliplatin for injection is not brittle. The quality of oxaliplatin for injection is consistent with its official standard.
出处
《中国药业》
CAS
2006年第14期28-29,共2页
China Pharmaceuticals
关键词
注射用奥沙利铂
处方筛选
制备
质量考察
oxaliplatin for injection
prescription optimization
preparation
quality investigation
