摘要
目的了解高血压伴颈动脉粥样硬化患者的动态血压变化。方法对186例高血压患者行超声检查双侧颈动脉,分成颈动脉正常组;颈动脉内膜增厚但无颈动脉斑块组和颈动脉内膜增厚有颈动脉斑块形成组。监测24h动态血压。结果颈动脉内膜增厚病人,无颈动脉斑块组和有颈动脉斑块组的最大收缩压、最小收缩压、平均收缩压、日间平均收缩压、夜间平均收缩压均高于颈动脉正常组,差异有统计学意义(P<0.05);无颈动脉斑块形成组和有颈动脉斑块形成组之间差异无统计学意义(P>0.05);最大舒张压、最小舒张压、平均舒张压、日间平均舒张压、夜间平均舒张压和全天平均动脉压在3组之间差异无统计学意义(P>0.05)。颈动脉内膜增厚病人组的异常昼夜节律的检出率和动态血压负荷值等于或超出40%的检出率高于颈动脉正常组。结论高血压患者动脉粥样硬化和有斑块患者的动态血压负荷值增大和昼夜节律异常。
Objectives To study the changes of ambulatory blood pressure in essential hypertensive patients with different degree of carotid artery atherosclerosis. Methods 186 hypertensive patients underwent ultrasound examinations of carotid artery. We classified them into three groups： A-normal carotid artery group; B- carotid artery atherosclerosis with no intima thicken group; C- carotid artery atherosclerosis with intima thicken group. They all monitored 24 hour ambulatory blood pressure. Results 24 h SBPmax, 24 h SBPmin, day SBP mean, night SBP mean of B and C groups were higher than those of A group. There was no difference between B and C groups of 24 h SBPmax,24 h SBPmin,day SBPmean,night SBPmean. There was no difference between three groups of 24 h DBPmax, 24 h DBPmin, day DBPmean, night DBPmean,24 h MAP. The check rate of abnormal rhythm of blood pressure of B and C groups were higher than it of A group. The charge of ambulatory blood pressure ≥40 % of B and C groups were higher than those of A group. Conclusions The patients with high SBP were lead to carotid artery atherosclerosis. The charge of ambulatory blood pressure and the abnormal rhythm of blood pressure may be the cause for the formation of artery atherosclerosis in patients with essential hypertension.
出处
《岭南心血管病杂志》
2006年第4期251-253,共3页
South China Journal of Cardiovascular Diseases
关键词
高血压
动脉粥样硬化
动态血压
Hypertension
Carotid artery atherosclerosis
Ambulatory blood pressure
