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侧链含酯键的聚阳离子/羧甲基纤维素钠复合物纳米粒子的制备

Polyelectrolyte Complex Nanoparticles Prepared from a Novel Ester Bonds-Containing Polycation and Sodium Carboxymethylcellulose
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摘要 合成了一种新型可降解阳离子聚(氨乙酰氧乙基天冬酰胺)盐酸盐(PAAEA.HCl),并由PAAEA.HCl与羧甲基纤维素钠(NaCMC)水溶液通过静电相互作用得到纳米级聚电解质复合物.同时,研究了该聚电解质溶液浓度、性质、离子强度对复合物粒径和ξ-电位的影响.结果表明,在蒸馏水中,聚电解质浓度为1.0 mmol/L、电荷比n+/n-为2制备得到的聚电解质复合物纳米粒子平均粒径为110 nm,ξ-电位为35 mV,其溶液在4℃时可以稳定保存一周. A novel polycation, poly(a was prepared starting from L-aspartic acid. minoacetyloxyethylaspartamide) hydrochloride (PAAEA · HCI) The polyelectrolyte complex nanoparticles were ξ-ormed via the electrostatic interaction between poly (aminoacetyloxy-ethylaspartamide) hydrochloride and sodium carboxymethylcellulose. The effects of polyion concentration, solution properties, solution ionic strength on the sizes and zeta potentials of the formed nanoparticles were investigated. The size and ξ-potential of nan oparticles, prepared from a solution of poly(aminoacetyloxyethylaspartamide) hydrochloride in water (1.0 mmol/L) and a solution of sodium carboxymethylcellulose in water (1.0 mmol/L) at n+/n- =2, are 110 nm and 35 mV, respectively. Thus obtained nanoparticles are stable within one week at 4 ℃.
出处 《武汉大学学报(理学版)》 CAS CSCD 北大核心 2006年第4期385-390,共6页 Journal of Wuhan University:Natural Science Edition
基金 国家自然科学基金资助项目(20204009 20474045) 教育部留学回国人员基金资助项目(20315) 湖北省新型反应器与绿色化学工艺重点实验室开放课题资助项目
关键词 聚阳离子 羧甲基纤维素钠 聚电解质复合物 纳米粒子 polycation sodium carboxymethylcellulose polyelectrolyte complex (PEC) nanoparticles
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参考文献12

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