摘要
目的:研究强直性脊柱炎湿热血瘀证的辨证要素,探讨证候的研究方法。方法:把中医辨证理论方法与流行病学调研方法、多元统计分析方法有机地结合,选取就诊的强直性脊柱炎患者进行调查研究并对资料进行统计学处理。结果:聚类分析发现,强直性脊柱炎的主要症状为:腰脊活动受限、晨僵、腰骶疼痛、脊背疼痛。Logistic分析得出湿热血瘀证候诊断的主要症状,对证候的归属进行判断,以预测概率0.5为判别分界点,总正确率为88.1%。判别式分析得出对湿热血瘀证诊断有帮助的症状,并建立判断函数,符合率为89.2%,灵敏度为77.3%,特异度为92.7%,Kappa值为0.695。结论:应用临床流行病学的调查方法并结合统计学分析进行证候研究,包括中医辨病和辨证要素的研究是可行的。
Objective：To study on key-factor of syndrome differentiation for damp-heat and blood stasis syndrome of akylosing spondylitis. Methods： By organically combining theories and methods of TCM syndrome differentiation with epidemiologic investigation methods and polyphyletic statistical analysis method,patients of akylosing spondylitis were selected for investigation and study, and data was statistically processed. Results：It was found by clustering analysis that main symptoms of akylosing spondylitis were limitation of lumbar spinal cord movement ,morning rigidity,lumbasacral pain, pain in spinal cord and the back. Main symptoms of damp-heat and blood stasis syndrome were attained by logistic analysis, and classification of syndrome was judged. Taking prediction probability of 0.5 as judging point,the total correct rate was 88.1%. Discriminant analysis attained symptoms helpful to diagnosis of damp-heat and blood stasis syndrome,and established judging function,with conforming rate of 89.20%,sensitivity of 77.3 % and specificity of 92.7% ,Kappa value of 0.695. Conclusion ： Application of clinical epidemiologic investigation method combined with statistical analysis to study on syndromes,including studies of key-factor of TCM disease differtentiation and syndrome differentiation ,is feasible.
出处
《中医杂志》
CSCD
北大核心
2006年第8期610-612,共3页
Journal of Traditional Chinese Medicine
关键词
脊柱炎
强直性/诊断
湿热/诊断
血瘀/诊断
Spondylitis, akylosing/diagnosis
Damp-heat/diagnosis
Blood stasis/diagnosis
