摘要
目的分析多发性梗死性痴呆(MID)的发病机制、临床表现、治疗、转归及预后。方法对于多发性梗死性患者采用长谷川修改量表(HDS)评分及Hachinsk缺血计分量表(HIS)评分,HDS<29.5分,HIS≥7分诊断痴呆,同时排除其他原因所致者。结果脑梗死后脑软化灶总体积超过50ml即可引起痴呆。MID发病相对迅速,呈阶梯性进展,临床表现主要为记忆力、计算力、情感障碍,晚期呈全面智能衰退。早期治疗可不同程度改善认知功能,重度痴呆病死率高,预后差。结论MID发病率、致残率、死亡率高,严重影响生活质量,积极治疗诱发脑血管病的相关疾病,减少脑血管病发病率即可减少本病发生。
Objective Analyze the pathogenesis, clinical behaviors, treatment, return and prognosis of the multi-infarct dementia （MID）. Methods The Hasegawa Dementia Scale （HDS） and the Hachinsk Ischaemic Scale （HIS） were adopted to score the multi-infarct patients. Excluding other causes, if HDS〉29.5, HIS〉7, the illness would be diagnosed as the dementia. Results A damage of 6-8×104/mm3 of the brain tissue would cause the dementia. MID came on relatively rapid and developed like stairs. The clinical behaviors were mainly the disturbances of the memory, the calculation and the emotion, and the full decline of the brainpower in the advanced stage. The early stage treatment could improve the cognitive function at different degrees. Heavy dementia had a high death rate and a bad prognosis. Conclusions MID had a high incidence rate, a high disability rate and a high death rate, which severely affected the quality of llfe. Active treatments of the correlative disease causing the brain blood vessel diseases and a reduction of the incidence of the brain blood vessel diseases could reduce the occur of this illness.
出处
《基层医学论坛》
2006年第9期773-774,共2页
The Medical Forum
关键词
多发性脑梗死
痴呆
脑代谢活化剂
脑循环改善药
Multi-infarct dementia Dementia Brain metabolizing activation dosage Brain circulation improvement medicine
