摘要
37例晚期肺癌接受平消胶囊合并化疗药物治疗,与同期单纯化疗的28例晚期肺癌对照,有效率分别是54.0%和35.7%(P>0.05)。治疗组化疗后外周血白细胞减少Ⅱ度以上发生率为43.2%,对照组为78.6%,有显著差异(P<0.01)。部分患者在服用平消胶囊前及2疗程后检测外周血 T 细胞亚群及 NK 细胞活性,发现服用平消胶囊2疗程后 OKT_4^+、OKT_4^+/OKT_8^+,均显著升高(P<0.01),NK 活性也明显增高(P<0.05)。提示:平消胶囊对晚期肺癌的化疗可能有一定的增效作用,能减轻血液毒副作用。通过提高化疗后患者外周血 NK 活性及部分纠正 T 细胞亚群的失衡状态,改善患者的细胞免疫功能,起到了补气扶正的作用。
A control study was made with 37 cases of late lung cancer treated with Pingxiao Capsule and chemotherapy compared with 28 cases of late lung cancer treated with only chemotherapy,the effective rates being 50.0% and 35.7% respectively(P>0.05).In the treatment group,the incidence rate of second degree reduction of leuko- cyte in the peripheral blood after chemotherapy was 43.2%,while this figure was 78.6% in the control group(P <0.01).After 2 courses of treatment with Pingxiao Capsule,it was discovered that OKT_4^+ and OKT_4^+/OKT_8^+ rose markedly(P<0.01)and NK activity also increased significantly(P<0.05).This suggests that Pingxiao Capsule has certain enhancing effect in the chemotherapy for late lung cancer and can reduce toxic side effect.By increasing the NK activity in the peripheral blood after chemotherapy and partly rectifying the imbalance of T- cell subgroup,the patient's immunity is improved and the body resistance is strengthened.
出处
《南京中医药大学学报》
CAS
CSCD
1996年第2期14-16,共3页
Journal of Nanjing University of Traditional Chinese Medicine
关键词
中医药疗法
平消胶囊
药物疗法
肺肿瘤
TCM treatment
late lung cancer
Pingxiao Caosule
chemotherapy
