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严重心功能衰竭患者血浆脑钠肽水平和预后的关系 被引量:4

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摘要 目的:探讨严重心功能衰竭(CF)患者血浆脑钠肽(brainnatriureticpeptide,BNP)水平在治疗前后的变化及其与预后的关系。方法:对在我院住院的心功能Ⅳ级的CF患者进行研究,根据住院期间是否死亡,分为死亡组和非死亡组,将两组病人的年龄、左室射血分数(LVEF)、治疗前后的血浆BNP浓度进行比较。结果:死亡组和非死亡组年龄、LVEF的比较,差异无显著性(P>0.05)。死亡组血浆BNP浓度高于非死亡组,两者差异有显著性(P<0.01)。死亡组血浆BNP浓度治疗后高于治疗前,非死亡组血浆BNP浓度治疗后较治疗前明显降低,两者差异均有显著性(P<0.01)。结论:血浆BNP水平越高,预后越差。治疗后血浆BNP浓度无下降,反而升高者,预后极差。血浆BNP浓度是评价严重CF患者预后的敏感指标,具有重要的临床价值。
作者 薛丽珠
出处 《实用医学杂志》 CAS 2006年第17期2002-2003,共2页 The Journal of Practical Medicine
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