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经涎腺投递基因疫苗的研究进展 被引量：1

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摘要 基因疫苗能够诱导机体产生较强和持久的免疫应答,制作成本低,运输、储存和使用方便,具有潜在应用价值。常规基因免疫途径有肌肉注射、皮内注射、静脉内注射、腹腔内注射、皮下注射、粘膜免疫等。涎腺作为外分泌腺体,其解剖特点特别适用于基因疫苗的投递。经涎腺投递基因疫苗是近些年涌现出的新的免疫方式,具有免疫原性强、安全性好等优点。经涎腺投递的基因疫苗不仅能够诱导体液免疫和细胞免疫,还能诱导强烈的黏膜免疫。
作者 海波 王松灵
机构地区 首都医科大学口腔医学院基因治疗分子生物学实验室 现在首都医科大学附属北京友谊医院口腔科
出处 《北京口腔医学》 CAS 2006年第3期223-225,共3页 Beijing Journal of Stomatology
关键词 基因疫苗 涎腺 静脉内注射 腹腔内注射 外分泌腺体 免疫应答 肌肉注射 免疫途径 皮内注射 皮下注射
分类号 R392 [医药卫生—免疫学]
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参考文献22

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共引文献6

同被引文献22

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北京口腔医学
2006年 第3期

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