摘要
目的观察尿路感染病原菌的菌群分布及对药物的反应性。方法对该院110例真性菌尿患者尿培养结果进行分析。结果清洁中段尿培养阳性率仅为28.9%。尿路感染的病原菌仍以G-杆菌为主,占82.7%,G+球菌占12.7%,真菌占4.6%。药敏结果显示氨苄西林对G-杆菌及其中的大肠埃希氏菌耐药率最高,阿米卡星、头孢他啶等对G-杆菌有较高的敏感性,亚胺培南对肠杆菌科保持着高度敏感性。G+球菌对红霉素、青霉素、环丙沙星及庆大霉素的耐药率均在50.0%以上,对替考拉宁、万古霉素的耐药率较低。结论G-杆菌在尿路感染中仍占绝对优势;合理使用抗生素对有效控制尿路感染和避免耐药菌株的产生尤为关键。
[Objective] To investigate the pathogen constitution and antibiotic resistance in urinary tract infection （UTI）. [Methods] Analysis was carried on the data of 110 culture-positive patients with UTI. [Results] The positive rate of clear midstream urine culture only was 28.9%. And among all the pathogenic bacteria, Gram-Negative bacilli, which was still the most frequent pathogen in UTI, accotmted for 82.7%, Gram-positive cocci accotmted for 12.7% and fungi occupied 4.6%. The drug susceptibility test results indicated that Gram-negative baeiUi and Escherichia coli had the highest resistance rate to AmpieiUin, Gram-Negative bacilli were susceptible to Amikacin and Ceftazidime, and Enterobaeteriaceae had high suseeptivity to Irnipenem. The drug resistance rate of Gram-positive cocci exceeded 50% to Erythromycin, Benzylpenicillin, Ciprofloxacin, Gentamicin, while it was low to Teicoplanin and Vancomycin. [Conclusion] Gram-negative bacilli remains the most frequent pathogen in UTI, and the rational use of antibiotics is critical to the effective control of UTI and to the prevention of emerging drug-resistant bacteria strains.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2006年第15期2371-2373,2376,共4页
China Journal of Modern Medicine
关键词
尿路感染
尿液细菌培养
细菌耐药
urinary tract infection
urinary bacterial culture
antibiotic resistance
