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皮下泵化疗在转移性肝癌中的应用

PUMP IMPLANTATION CHEMOTHERAPY FOR ADVANCED HEPATOCELLULAR CARCINOMA
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摘要 目的:探讨肝动脉加门静脉灌注化疗在转移性晚期肝癌中的价值。方法:50例转移性肝癌患者分成三组。一组肝动脉加门静脉灌注化疗20例;二组肝动脉灌注化疗16例;三组门静脉灌注化疗14例。3组化疗方案、剂量、间隔时间均相同。结果:肝癌有效率(CR+PR)一组、二组、三组分别为70.0%、50.0%、28.6%。1年、2年生存率一组为75.0%、45.0%;二组为56.3%、31.2%;三组为50.0%、28.6%。结论:肝动脉门静脉双泵灌注化疗治疗转移性晚期肝癌疗效优于单纯门静脉化疗。 Objective:To study the value of infusion chemotheropy by pump via hepatic artery or portal vein or both for advanced hepatocellular carcinoma. Methods:Fifty patients of advanced hepatocellular carcinoma were divided into three groups: 1. Group Ⅰ , both hepatic artery and portal vein implantation chemotherapy (20 patients). 2. Group Ⅱ :hepatic artery implantation Chemotherapy(16 patients). 3. Group Ⅲ :portal vein implantation chemotherapy (14 patients). Results: Response rate was 70.0% in group Ⅰ , 50% in group Ⅱ and 28. 6% in groupⅢ. The one-year,two-year survival rates were 75. 0%,45. 0% in group Ⅰ ,56.3%,31.2% in group Ⅱ and 50.0%,28. 6% in group Ⅲ . Conclusion:Both hepatic artery and portal vein implantation chemotherapy is effective in treating advanced hepatocellular carcinoma. It is better than portal vein pump implantation chemotherapy alone.
出处 《承德医学院学报》 2006年第3期244-245,共2页 Journal of Chengde Medical University
关键词 肝肿瘤 药物灌注疗法 肝动脉 门静脉 Liver neoplasms Infusion chemotherapy Hepatic artery Portal vein
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