摘要
目的:探讨松花粉对D-半乳糖衰老大鼠肝脏抗氧化能力的影响。方法:D-半乳糖连续腹腔注射制作亚急性衰老的大鼠模型,采用生物化学方法检测各组大鼠肝组织匀浆中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)的活力以及总抗氧化能力(T—AOC)。结果:D-半乳糖衰老大鼠SOD活力、GSH-PX活力和T—AOC均明显下降,与正常大鼠比较差异显著(P<0．01);松花粉灌胃给药后SOD活力、GSH—PX活力和总抗氧化能力均显著提高;松花粉的效果好于VE(P<0．01)。结论:松花粉可显著提高亚急性衰老大鼠肝脏抗氧自由基的能力,具有一定延缓衰老的作用。
Objective ：To explore the influence of Pine Pollen on anti-oxidative ability in liver of D-gal aging rats. Methods： The sub-acutely aging model rats were made by intraperitoneal injection of D-gal continually. Biochemical methods were used to detect T-AOC, SOD and GSH-PX activities in liver tissue bomogenate of each group. Results： T-AOC, SOD and GSH-PX activities of rats in aging model group significantly decreased compared with normal rats （P〈0. 01）; While the three indexes were remarkably increased after taking Pine Pollen, and there was statistically difference between Pine Pollen and VE （P〈 0. 01）. Conclusions： Pine Pollen could obviously increase the anti-oxidative ability of liver, and has certain anti-aging effects.
出处
《承德医学院学报》
2006年第3期233-235,共3页
Journal of Chengde Medical University
