摘要
目的:研究高压氧治疗对甲亢131I内照射治疗后早发甲低患者的血清甲状腺激素水平的影响,探索甲状腺功能低下的新的治疗方法。方法:早发甲低患者42人,随机分为高压氧治疗组和对照组,每组21人,治疗前后测定血清T3、T4、TSH水平。结果:治疗组和对照组血清T3、T4水平均较治疗前明显升高,但实验后,两组血清T3、T3水平比较均未见统计学差异(P>0.05);治疗组和对照组血清促甲状腺素分泌水平均下降,治疗组下降幅度较对照组明显,且差异显著(P<0.05)。结论:高压氧干预可有效促进甲状腺组织功能恢复,可能是治疗临床早发甲低的新的途径。
Objective To study the influence of hyperbaric oxygen on hypothyroidism after 13l I therapy. Methods Fourty - two patients with early hypothyroidism after ^131I therapy were randomly divided into two groups the hbo group （n = 21 ） and the non- hbo group （ n = 21 ）. Serum T3, T4 and TSH levels were measured twice （ four months apart） with CLIA in both groups. Results Serum T3 and T4 levels were increased significandy in both groups after the four months course of low - dosage thyroid hormone replacement but there were no significantly differences between the final levels in the two groups （ P 〉 0.05 ）. TSH levels were lowered significantly in both groups （ both P 〈 0.05 ）, however, the magnitude of lowering was slgnifieantly larger in the hbo group than that in the non - hbo group （P 〈 0.05）. Conclusion Hyperbaric oxygen therapy might be a potential useful means for treatment of early hypothyroidism after administration of ^131I.
出处
《放射免疫学杂志》
CAS
2006年第4期333-335,共3页
Journal of Radioimmanology
