摘要
目的:探讨了老年慢性支气管炎患者治疗前后血清IGF-Ⅱ和NO的水平及临床意义。方法:分别应用放免法和生化法对42例老年慢性支气管炎患者进行了血清IGF-Ⅱ和NO水平检测,并与30例正常老人作比较。结果:老年慢性支气管炎患者在治疗前血清IGF-Ⅱ水平非常显著地高于正常人组(P<0.01),而NO水平则显著低于正常人组(P<0.01),经治疗后2周与正常人比较仍有差异(P<0.05)。结论:检测老年支气管炎患者血清中IGF-Ⅱ和NO水平对了解病情、观察预后均有重要的临床价值。
Objective To study the clinical significance of changes of serum IGF-Ⅱ and NO levels after treatment in elderly patients with chronic bronchitis. Methods Serum IGF-Ⅱ （with RIA） and NO （with Biochemical method） levels were measured in 42 elderly patients with chronic bronchitis both before and after treatment as well as in 30 controls. Results Before treatment in the patients the serum IGF -Ⅱ levels were signifiantly higher than those in controls （ P 〈 0.01 ）, while the NO levels were significantly lower （P 〈0.01 ）. After two weeks of treatment, the levels though dropped markedly, lemained higher than those in controls （P 〈0. 05 ）. Conclusion Serum IGF-Ⅱ and NO levels changes could reflect the disease status as well as the progress of diseases.
出处
《放射免疫学杂志》
CAS
2006年第4期276-277,共2页
Journal of Radioimmanology
关键词
老年慢性支气管炎
胰岛素样生长因子-Ⅱ
一氧化氮
chronic bronchitis in elderly patients, insulin -growth factor-Ⅱ （IGF-Ⅱ ）, nitric oxide
