摘要
目的探讨脂脉舒与辛伐他汀合用对高脂血症病人的治疗效果。方法将215例高脂血症病人随机分为治疗组(脂脉舒加辛伐他汀组)和对照组(辛伐他汀组)进行治疗,于治疗前后检测其血脂和血糖等指标。结果治疗组总有效率为98.2%,明显优于对照组的89.5%(P<0.01);两组均能明显降低高脂血症病人总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL-C)、尿酸(UA)和C反应蛋白(CRP)(P<0.01或P<0.05),而治疗组还能明显升高HDL-C(P<0.05),并能抑制血糖(Glu)和丙氨酸转氨酶(ALT)水平的升高(P<0.01)。结论脂脉舒与辛伐他汀联合应用能整体地、多方面地调节高脂血症病人的代谢紊乱。
Objective To observe the effect of simavastatin with Zhimaishu for hyperlipidemia. Methods Two hundred and fifteen patients with hyperlipidemia were randomly divided into the treatment group （simavastatin with zhimaishu） and control group （simavastatin group）. The blood indexes （lipids and glucose etc） were detected pre- and post - therapy. Results The effects in treatment group were superior to that in control group （P〈0.01）. Both simavastatin and simavastatin with Zhimaishu obviously could decrease the level of TC, TG, LDL- C, UA and CRP （P〈0.01 or P〈0.05）. But the later could increase HDL - C content obviously （P〈0.05） and inhibit the rise in glucose and ALT （ P〈 0.01 ）. Conclusion Simavastatin with Zhimaishu might adjust the disturbance of metabolism in hyperlipidemia.
出处
《中西医结合心脑血管病杂志》
2006年第1期33-34,共2页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金
广东省中医药局立项基金项目(No.401045)
关键词
脂脉舒
辛伐他汀
高脂血症
Zhimaishu
Simavastatin
hyperlipidemia
