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加替沙星治疗老年社区获得性肺炎的临床评价 被引量:7

Clinical evaluation of gatifloxacin on acquired pneumonia in the elderly
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摘要 目的 评价加替沙星治疗老年社区获得性肺炎的有效性和安全性。方法以加替沙星静脉滴注为治疗组,每天400mg;头孢曲松钠静脉滴注为对照组,每天2.0g,疗程均为7~10d。对两组治疗老年社区获得性肺炎的疗效和安全性进行随机观察。结果治疗组和对照组的总有效率分别为95.33%和92.11%,细菌清除率分别为87.32%和83.33%,不良反应发生率分别为6.67%和7.24%。结论加替沙星静脉滴注治疗老年社区获得性肺炎疗效良好,不良反应少,使用安全。 Objective To evaluate the efficacy and safety of gatifloxacin in treatment of senile patients with community - acqired pneumonia(CAP). Methods A prospective, comparative study on senile CAP patients was carried out. The patients were either intravenously given gatifloxaein 200mg twice daily (treatment group) or eeftriaxone 2.0g once daily ) the control group) for a course of 7 - 10 days. Results Clinical total effective rate in patients receiving gatifloxaein was 95.33 % and 92.11% in patients receiving eeftriaxone; the bacterial eradication rates were 87.32% in the treatment group and 83.33% in the control group, respectively. The clinical adverse effect rates were 6.67% in the treatment group and 7.24% in the control group, respectively. Conclusion Gatifloxaein is excellently effective and safe for treatment of senile CAP patients with light adverse reactions.
出处 《中国热带医学》 CAS 2006年第8期1449-1450,共2页 China Tropical Medicine
关键词 加替沙星 社区获得性肺炎 头孢曲松钠 老年 Gatifloxacin Community - aequiredpneumonia Ceftriaxon The elderly
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