摘要
本文采用放免法检测了经临床确诊为肝硬化36例、原发性肝癌34例的血清β_2-微球蛋白含量,结果阳性率分别为77.7％及79.4％。提示β_2-微球蛋白检测对肝硬化、原发性肝癌无鉴别意义;对原发性肝癌β_2-微球蛋白敏感性高,特异性差,须结合其他的有关血清学检测结果综合判断。
The serum concentration of β_2-microglobulin in 36 patients withcirrhosis of the liver and 34 patients with primary hepatic carcinomawas measured by radio-immuno-assay (RIA), the positive rate being77.7% and 79.4 % respectively. These results suggest that β_2-microglobu-lin bears no significance in differeintiation of cirrhosis and carcinoma.β_2-microglobulin had a high sensitivity but a low specificity in primaryhepatic carcinoma. Therefore the diagnosis should be considered byother seralogical data.
关键词
Β2微球蛋白
肝硬变
肝肿瘤
β_2-microglobulin(β_2M)
cirrhosis of the liver
primary hepatic carcinoma
