摘要
通过二氮磷酸－Ｏ－（１－氧－２，２，６，６，－四甲基－４－哌啶醇）酯分别与四甘醇、三甘醇、二甘醇、１，６－己二醇、１，８－辛二醇、Ｎ－乙基二乙醇胺、Ｎ－正丁基二乙醇胺缩聚，制得七个含稳定氮氧自由基（ＴＥＭＰＯ）的聚磷酸酯．对这些新的聚磷酸酯进行了结构表征，并测试了部分聚合物的纵向弛豫性能．
Seven spin-labeled polyphosphates were synthesized by the polycondensation of O-(1 -oxyl-2, 2, 6, 6-tetramethyl-4-piperidyl) phosphoric acid dichloride with tetraethylene glycol, triethylene glocol, diethylene glycol, 1, 6-hexanediol, 1,8-octandiol, N-ethyldiethanolamine and N-butyldiethanolamine, respectively.The structures of these stable nitroxyl-labeled polyphosphates were characterized by IR, UV, ESR, VPO and Elemental analysis. The relaxivity (R_i) of polyphosphate 3a,3c and 3d was investigated.
出处
《波谱学杂志》
CAS
CSCD
1996年第5期417-422,共6页
Chinese Journal of Magnetic Resonance
基金
国家教委博士点基金
中科院武汉物理所波谱与原子分子物理国家重点实验室基金
关键词
氮氧自由基
自旋标记
聚磷酸酯
Nitroxide
Spin-labeling
Polyphosphate
MRI contrast agent
Relaxivity
