摘要
用80只 SD 大鼠分设8组,10只大鼠作为正常对照;70只诱发慢性胃炎,其中10只大鼠作为模型组。20只大鼠为胃炎冲剂预防组;治疗性研究包括4组,每组10只大鼠分别用生理盐水、三九胃泰及高、低剂量的胃炎冲剂处理30天。用^(113m)InCl_3研究胃血流,用生化法测胃窦粘膜的 DNA 含量,实验组的所有结果与正常或生理盐水处理的对照组进行比较。结果表明模型动物的胃血流明显增多,用胃炎冲剂进行预防和治疗处理则显然可使之恢复。
80 SD rats were divided into 8 groups,10 rats were used as normal control,70 rats were induced chronic gastritis with alcohol and sodium deoxycholate infusion per oral for 90 days.Among which 10 rats were model group,20 animals belong to preventive group treated with “Wei Yan Chongji” during inducing period simultaneously;and the therapeutic study included 4 groups,each of them had 10 rats,which were treatedwith saline or “San Jiu Wei Tai” and or with high or low doses of“Wei Yan Chongji” respectively for 30 days.The gastric blood flow was studied with ^(113m)InCl_3 and the DNA content of antral mucosa was measured with biochemical method.All the results of experimental groups were compared with normal saline treated control.It wasdemonstrated that the gastric blood flow increased seriously in the model animals,and subsided significantly in preventive and therapeutic groups with “Wei Yan Chohgji” treatment.
关键词
胃炎
胃血流
胃窦DNA
胃炎冲剂
experimental chronic gastritis
gastric blood flow
DNA content in antral mucosa
"Wei Yan Chongji"
"San Jiu Wei Tai"
