摘要
目的探讨妊娠高血压病人心率变异性(HRV)与血清甲状腺激素的关系。方法应用Century3000型闪光卡型动态心电图自动分析系统对60例妊娠高血压疾病病人(观察组)及60名正常妊娠(对照组)HRV频域及时域进行分析,同时用放免法测定甲状腺激素水平。结果妊娠高血压疾病病人中,血清三碘甲状腺原氨酸(T3)减低(P<0.05),而反三碘甲状腺原氨酸(rT3)水平升高(P<0.01);HRV指标24h正常R-R间期标准差(SDNN)、24h相邻R-R间期差值的均方根(rMSSD)、低频成分(LF)和高频成分(HF)水平降低P<0.05),而LF/HF升高(P<0.05)。结论妊娠高血压疾病病人存在继发性甲状腺代谢紊乱,低T3及高rT3水平可作为评价妊娠高血压疾病病人及预后的指标之一。
Objective To explore the relation between rate variability （HRV） and thyroid hormone in patients （pts） with pregnancy hypertension. Methods The level of serum T3 and rT3 were tested in 60 pts with pregnancy hypertension and 60 controls with normal pregnancy. The data of SDNN, rMSSD, LF and HF were collected. Results The serum T3 reduced in pts with pregnancy hypertension （P 〈 0.05）. And level of rT3 increased （P〈O, 01）. HRV index SDNN,rMSSD, LF and HF reduced （P〈0.05） and the ratio of LF/HF increased （P〈0.05）. SDNN, rMSSD LF and HF decreased in pts with pregnancy hypertension. Conclusion T3 decreased and rT3 increased in pts with pregnancy hypertension. The result suggested that autonomous nerve regulation function was damaged obviously in pts with pregnancy hypertension.
出处
《中西医结合心脑血管病杂志》
2006年第5期382-384,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词
妊娠高血压
甲状腺激素
心率变异性
动态心电仪
pregnancy hypertension
thyroid hormone
heart rate variability
holter monitoring
