摘要
用大孔吸附树脂等方法分离丙酰螺旋霉素（ＰｒｏＳＰＭ），除得到以前分离的丙酰螺旋霉素ＩＩＩ（ＰｒｏＳＰＭＩＩ）外，又得到一个新成分。根据其理化性质和波谱［ＵＶ，ＨＲＭＳ，１ＨＮＭＲ，１３ＣＮＭＲ（含ＤＥＰＴ）和１Ｈ１３ＣＣＯＳＹ］数据，并与ＰｒｏＳＰＭＩＩ比较，ＰｒｏＳＰＭＩＩ仅Ｃ３酰基不同，命名为丙酰螺旋霉素ＩＩ（ＰｒｏＳＰＭＩＩ）。
Component A and B were isolated from propionyl spiramycin (Pro SPM) by means of column chromatography with macroreticular resin. Their physical and chemical properties were determined. On the basis of analytical data component A was shown to be identical with the previously reported Pro SPM III. The structure of component B was elucidated and designated as Pro SPM II. It is a new antibiotic. The only difference between A (Pro SPM III) and B (Pro SPM II) is the presence of a C 3 O Pro in A in contrast to the presence of a C 3 OAc in B.
出处
《药学学报》
CAS
CSCD
北大核心
1996年第8期597-601,共5页
Acta Pharmaceutica Sinica
