摘要
我国散发性戊型肝炎病毒细胞培养分离株的鉴定１００８５０北京军事医学科学院微生物流行病研究所苑锡同，李晓萸，黄如统，李德荣关键词肝炎病毒，戊型；病毒细胞培养；病毒鉴定；聚合酶链反应；核酸杂交中国图书资料分类号Ｑ９３９．４我国戊型肝炎存在着流行和散发两种...
This experiment aims to study the significance of unbalance of endothelial mediators resulting from damage and dysfunction of endothelial cells in coronary heart disease (CHD).NO 2 (metabolite of NO),endothelin (ET) and circulating endothelial cells(CEC) were observed in the peripheral blood of 48 patients with coronary heart disease.It was found that the mean serum NO (μg/L) of CHD patients was significantly lower than that of the control subjects (0 5007±0 3038 vs .1 10675±1 2928, P <0 01);the mean ET and CEC were significantly higher in CHD patients than in control subjects (ET 166 385±59 795 vs . 56 584±6 388, P <0 01,CEC 12 5±3 8 vs . 3 5±0 49, P <0 01) and were in consistent with the severity of CHD.NO was negatively correlated with ET.It proved that there existed damage of EC and unbalance of endothelial mediator.Our results showed that the changes of CEC,NO and ET were involved in the course of CHD,and the parameters might be improved by captopril administration.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
1996年第4期284-285,共2页
Medical Journal of Chinese People's Liberation Army
关键词
戊型肝炎
病毒细胞培养
病毒
鉴定
PCR
核酸杂交
coronary disease
nitric oxide
endothelin
circulating endothelial cells
captopril
