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CYP2C9基因多态性的分子学机制、基因型检测及对药物代谢的影响 被引量:4

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作者 赵树进 袁进
出处 《广东医学》 CAS CSCD 北大核心 2006年第8期1268-1270,共3页 Guangdong Medical Journal
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参考文献15

  • 1GERBAL CHALOIN S,DAUJAT M,PASCUSSI J M,et al.Transcriptional Regulation of cyp2c9 Gene[J].J Biol Chem,2002,277(1):209-217.
  • 2PEYVANDI F,SPREAFICO M,SIBONI S M,et al.CYP2C9 genotypes and does requirements during the induction phase of oral anticogulant therapy[J].Clin Pharmacol Ther,2004,75(3):198-203.
  • 3李健,文思远,王睿,陈昆,方翼,裴斐,王升启.细胞色素P450CYP2C9基因多态性对甲苯磺丁脲代谢动力学的影响[J].药学学报,2005,40(8):695-699. 被引量:22
  • 4LEE C R,GOLDSTEIN J,PIEPER J A.Cytochrom P450 2C9 polymorphisms:a comprehensive review of the in-vitro and human data[J].Pharmacogenetics,2002,12(3):251-263.
  • 5XIE H G,PRASAD H C,KIM R B,et al.CYP2C9 allelic variants:ethnic distribution and functional significance[J].Adv Drug Deliv Rev,2002,54(10):1257-1270.
  • 6ALLABI A C,GALAJL,HORSMANSY,etal.Functional impact of CYP2C9* 5,CYP2C9*6,CYP2C9* 8,and CYP2C9* 11 in viv among black Africans[J].Clin Pharmacol Ther,2004,76(2):113-118.
  • 7SCORDO M G,PENGO V,SPINA E,et al.Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance[J].Chin Pharmacol Ther,2002,72 (6):702 -710.
  • 8VANDER WEIDE J,STEIJNS L S,VAN WEELDEN M J,et al.The effect of genetic polymorphism CYP2C9 on phenytoin dose requirement[J].Pharmacogenetios,2001,11 (4):287-291.
  • 9NIEMI M,CASCORBI I,TIMM R,et al.Glyburide and glimepiride pharmacokinrtics subjects with different CYP2C9 genotypes[J].Clin Pharmacol Ther,2002,72(3):326-332.
  • 10JETTER A,KINZIG-SCHIPPERS M,SKOTT A L,et al.CYP2C9 phenotying using loe-dose tolbutamide[J].Eur J clin Pharmacol,2004,60(3):165-171.

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