摘要
实验模拟骨在功能活动过程中细胞外环境压力的变化这一生理过程，给实验组离体培养成骨细胞提供间断气体压力变化（０．０９８ＭＰａ，１５分钟加压，１５分钟无压力，２周期／小时，每天加压８小时），发现成骨细胞数逐步增加，且碱性磷酸酶活性也明显增高，均与对照组有明显差异。结果提示，间断加压可促进离体培养成骨细胞的增殖与分化。
The experiment imitated the physiological changes of the cellular extemal circumstances, existed during skeletal functional movement, and supplied a intermittent compressive pressure(0.098 MPa, 15 minutes pressrue, 15 minutes relax, 2 cycles/one hour, 8 hours/day) to the osteoblasts of experiment al groups in vitro.It was discovered that the numbers of osteoblasts and the reaction of alkaline phosphatase in the experimental group were markedly elevated than that of the control groups. The results indicate that the intermittent compressive prssure is able to improve the proliferation and differentiation of the osteoblasts.
出处
《中国骨伤》
CAS
1996年第5期7-9,共3页
China Journal of Orthopaedics and Traumatology
基金
国家自然科学基金
关键词
间断压力
成骨细胞
培养
Intermittent compressive pressure Osteoblast in vitro
