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CPAP对单肺通气氧合的影响 被引量:5

Influence of Continuous Positive Airway Pressure on Arterial Oxygenation During One-lung Ventilation
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摘要 目的:探讨应用一种持续气道正压(CPAP)系统。对单肺通气下开胸病人的无通气肺施加持续气道正压,观察无通气肺接受持续气道正压时对动脉氧合的影响。方法:择期需在单肺通气下开胸手术病人20例,按美国麻醉医师协会(ASA)分级,Ⅰ~Ⅱ级;随机分为对照组(A组)和CPAP组(B组),每组各10例。A组在单肺麻醉期间非通气侧肺的支气管导管直接开口于大气中;B组单肺通气期间非通气侧持续给予CPAP(P=0.3kPa)。于仰卧双肺通气30min、仰卧单肺通气30min、侧卧单肺通气30min、60min、关闭胸腔双肺通气时,分别采取动脉血样做血气分析。结果:单肺通气后,B组氧合明显高于A组(P〈0.05)。结论:单肺通气期间,非通气侧持续给予CPAP,有助于提高氧合,减少肺内分流,可明显降低低氧血症的发生率。提高病人的安全性. Objective: To investigate pressure (CPAP) on arterial oxygenation the effects of non -ventilated lung with continuous positive airway during one -lung ventilation. Method: Twenty patients were randomized to receive thoracic operation. ASA Ⅰ - Ⅱ , were selected and were randomly divided into two groups : controlled group ( group A, n = 10 ) and observation group ( group B, n = 10 ). Group A : There were no ventilation on the non - ventilated lung open to the air; group B : CPAP was administered with O2 ( P = 0.3KPa ) via CPAP system on the non -ventilated lung during one lung ventilation. Blood gas analysis were determined at 30 min after two - lung ventilation ( TLV ) in the supine position, 30 min after one - lung ventilation ( OLV ) in supine position, 30 min and 60 min after OLV in lateral position and at the end of operation. Result: PaO2 in group B was increased significantly than that of in group A ( P 〈 0.05 ) during OLV. Conclusion: CPAP could improve the systemic oxygenation and reduce the intrapulmonary shunt and incidence rate hypoxemia during one lung ventilation.
出处 《河北医学》 CAS 2006年第8期733-735,共3页 Hebei Medicine
关键词 持续气道正压 单肺通气 血气分析 Continuous positive airway pressure One -lung ventilation Arterial oxygen partial pressure
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  • 1Pagel P S,Fu J L,Damask M C,et al.Desflurane and isoflurane produce similar alterations in systemic and pulmonary hemodynamics and arterial oxygenation in patients undergoing one-lung ventilation during thoracotomy[J].Anesth Analg,1998,87(4):800-807.
  • 2金清尘.单肺麻醉的低氧血症[J].中华麻醉学杂志,1997,17(11):699-700. 被引量:37
  • 3Bratzke E,Downs J B,Smith R A.Intermillent CPAP:a new mode of ventilation during general anesthesia[J].Anesthesiology,1998,89(2):334-340.

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