环糊精及其衍生物在口服给药制剂中的应用
摘要
环糊精(CD)及其衍生物是现代制剂中的重要辅料,在制剂领域有广泛的用途。CD及其新型衍生物具有不同的理化性质,选择合适的CD或CD衍生物可达到药物不同的释放要求。
出处
《医药导报》
CAS
2006年第8期806-807,共2页
Herald of Medicine
基金
重庆市应用基础研究基金资助项目[基金编号:(2003)7974]
参考文献10
-
1Caira M R, Robbertse Y. Structural characterization, physicochemical properties, and thermal stability of three crystal forms of nifedipine [J]. J Pharm Sci,2003,92(12) : 2519 -2533.
-
2Betlach L S, Bertuo J B. Bioavailability of carbamazepine: beta-cyclodextrin complex in beagle dogs from hydroxypropylmethylcellulose matrix tablets[ J ]. Eur J Pharm Sci,2004,22(2 - 3 ) : 201 -207.
-
3Fernandes C M, Veiga F B. Effect of the hydrophobic nature of triacetyl-β -cyclodextrin on the complexation with nicardipine hydrochloride: physicochemical and dissolution properties of the kneaded and spray-dried complexes[ J]. Chem Pharm Bull,2002,50(12):1597 - 1602.
-
4Fernandes C M, Ramos P. Hydrophilic and hydrophobic cycledextrins in a new sustained release oral formulation of nicardipine: in vitro evaluation and bioavailability studies in rabbits [ J ]. J Control Release,2003,88 : 127 - 134.
-
5Giuseppe T, Angela L. Encapsulation and release of the hypnotic agent zolpidem from biodegradable polymer microparticles containing hydroxypropyl-β-cyclodextrin [ J ]. Inter J Pharm, 2003,268 : 47 -57.
-
6Ikeda Y, Kimura K. Controlled release of a water-soluble drug, captopril, by a combination of hydrophilic and hydrophobic cyclodextrin Derivatives [ J ]. J Control Release,2000,66 : 271 - 280.
-
7Okimoto K,Tokunaga Y. Applicability of( SBE)7m-β-CD in controlled-porosity osmotic pump tablets(OPTs) [ J ]. Inter J Pharm,2004,286 : 81 - 88.
-
8Boulmedarat L, Piel G. Cyclodextrin-Mediated Drug Release from Liposomes Dispersed Within a Bioadhesive Gel [ J ]. Pharm Res,2005,22(6) : 962 -971.
-
9Yano H, Hirayama F. Colon-specific delivery of prednisolone-appended α-cyclodextrin conjugate: alleviation of systemic side effect after oral administration [J].J Control Release,2002,79:103-112.
-
10Kamada M, Hirayama F. Cycledextrin conjugate-based controlled release system: repeated- and prolonged-releases of ketoprofen after oral administration in rats [J]. J Control Release,2002,82 (2-3):407 -416.
-
1以药动学参数为终点评价指标的化学药物仿制药人体生物等效性研究技术指导原则(征求意见稿)[J].中国制药信息,2016,32(4):164-168.
-
2NOD公司纳米颗粒口服给药技术美国专利获准[J].中国新药杂志,2009,18(23):2235-2235.
-
3药品[J].中国医院院长,2014,0(22):21-21.
-
4刘鹏,战宏利,严倩倩,杨美琴,马仕洪,戴翚,肖磺,胡昌勤.中成药口服给药制剂及其原料药微生物污染相关性分析[J].药物分析杂志,2014,34(6):1068-1072. 被引量:24
-
5周嵩煜,宋嵩文,庞云娟.补肾强身胶囊微生物限度检查方法的探讨[J].中成药,2009,31(8):1306-1308. 被引量:3
-
6徐铮奎.功能性药物赋形剂研究开发新进展[J].中国制药信息,2013(6):12-16.
-
7徐敏,姜丽丽.非注射型胰岛素制剂[J].中国临床药学杂志,2002,11(5):318-320. 被引量:1
-
8邵珠德,刘元涛,李敏,高鹏,代龙.温胆汤两种现代制剂与传统汤剂化学指纹图谱的对比研究[J].中国医院药学杂志,2016,36(2):102-106. 被引量:4
-
9张鹏,赵鑫,范国荣.乳癖消现代制剂及其质量控制方法的研究进展[J].药学实践杂志,2014,32(1):16-18.
-
10赵勇,王晓荣.中药注射剂制备使用存在的问题及对策[J].实用医药杂志,2011,28(12):1089-1090. 被引量:1