摘要
麝香草酚是防腐剂和抗氧剂,也是一种食用香料。麝香草酚的合成方法不少,多数用间甲酚为原料,与含有异丙基的物质化合而成。通常要用高压、无水、耐腐蚀等反应条件,粗产品还要经过异构体分离和转位,工序比较复杂。我们开发了以香茅醛为原料,催化闭环成异胡薄荷醇,再催化脱氢成麝香草酚的方法,此法工艺简单,产品成本低。
A new synthetic method of thymol is developed, i.e. citronellal is catalyti-cally cyclized to isopulegol, which is then catalytically dehydrogenated to thymol. A new copper catalyst is also developed. The yield of thymol from the dehydrogenation of isopulegol is more than 80%. The catalyst can sustain a 100 day's service
