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脑形态测量学在神经系统疾病中的应用 被引量:1

Application of Voxel-Based Morphometry in Nervous System Disease
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摘要 基于体素的形态测量学(VBM)是一种脑形态学的测量方法,是应用解剖分割的程序和统计学的处理,它是通过对高分辨力、高清晰度、高灰白质对比的三维磁共振成像梯度回波T1加权像进行解剖分割,利用参数统计检验对分割的脑组织成分逐个进行体素分析比较,以定量的方法检测出脑组织成分的浓度或体积。国外应用VBM已达10年之久,主要在癫疒间方面进行了大量的研究,尤其是对颞叶内侧海马结构的测量。另外,VBM方法还应用于研究正常人群以及与年龄相关的脑结构,对全脑进行测定和比较,直接对原始数据进行统计分析,不受分析人员的主观影响。
作者 方方 邹丽萍
出处 《国际儿科学杂志》 2006年第4期230-232,共3页 International Journal of Pediatrics
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