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自身免疫性疾病患者血清ANA、抗ds-DNA、ENA多肽抗体检测245例结果分析

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摘要 目的:总结自身免疫性疾病时各抗体出现的规律,为临床诊断提供帮助。方法:对245例自身免疫性疾病患者及40例健康体检人员血清ANA、抗ds-DNA及ENA多肽抗体检测结果进行分析。结果:ANA、抗ds-DNA、ENA多肽抗体的检测对SLE的诊断有重要价值,多发性硬化症(SCL)ANA阳性率为70.5%,抗SCL-70阳性率只有52%,抗SS-A为干燥综合征(SS)特异性抗体,阳性率为73.9%,混合性结缔组织病(MCTD)抗U1-nRNP阳性率高达95.2%。结论:自身免疫性疾病时患者体内常存有一种或多种高效价的自身抗体,且不同疾病又有各自特异性抗体存在,需各项检测结果结合临床表现综合分析方可得出正确诊断。
作者 黄华健
出处 《现代医药卫生》 2006年第15期2371-2371,共1页 Journal of Modern Medicine & Health
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