摘要
目的观察-6°头低位卧床(HDT-6°)对肺循环血流的影响,并探讨其与肺弥散功能的关系。方法采用YK-10循环系统监测仪和HP2500超声诊断仪,对16名健康男性受试者90minHDT-6°卧床及21dHDT-6°卧床前、后及卧床不同时间肺循环血流、肺血容量、右心输出量等有关指标分别进行了测试。结果在90min卧床试验中,HDT-6°卧床肺血容量较卧床前坐位显著增加,随卧床时间延长,肺血容量渐减少,90min左右已显著少于平卧位水平。在21d卧床中,第3天最低,第7天测量仍显著低于卧床前平卧位对照值,以后保持相对稳定。起床后第3天平卧位测量仍低于卧床前。右心输出量在卧床第3天即显著下降,之后保持相对稳定,在起床第3天测量基本恢复;每搏量在卧床第7天显著降低,一直持续到起床第3天,而在这个阶段,心率则逐渐增加,卧床第20天和起床第1、3天均比卧床前有显著增加。结论头低位卧床使肺血流量增加的同时,增加了肺循环的灌注压,有肺间质水肿的潜在危害。同时肺动脉压升高,以及机体通过神经体液的自我调节,反过来减少了肺灌注,肺毛细血管血量的减少,有自我保护的作用。
Objective To observe the effects of head down tilt （HDT） 6° bed-rest on the pulmonary circulation blood perfusion.Method Sixteen health young men were selected as subjects.The indices of the pulmonary circulation blood peffusion,pulmonary blood volume （PBV）, right ventricular output volume were measured during 90 minute and 21 day HDT.Result The values of the pulmonary blood perfusion were higher as compared with those in supine position and in seat position during the 90 minute HDT. But they slightly decreased after the time, and lower than in supine position. During 21 day HDT, the values of the indices on the first day of HDT （HDT1） were significantly higher as compared with those in supine position （SP） before HDT, but the values decreased significantly from HDT3 to 1 day after HDT in supine position.Conclusion It would be a potential danger to interstitial edema of lungs because of pulmonary perfusion increase and pulmonary circulation perfusion pressure increase at the beginning of the HDT. The rising of the pulmonary arterial pressure would activate body neuro-humor＇s self-regulation, so that the pulmonary perfusion decreased, pulmonary capillary blood volume decreased conversely, belonging to a self-protection.
出处
《实用医药杂志》
2006年第7期825-828,共4页
Practical Journal of Medicine & Pharmacy
基金
载人航天科研基金921HY-2-1(0199307)
关键词
头低位卧床
肺循环血流
肺血容量
右心输出量
肺动脉压
Head down tilt bed-rest Pulmonary circulation blood perfusion Pulmonary blood volume （PBV） Right ventricular output volume Pulmonary arterial pressure
