摘要
用微米狭窄器在12条麻醉开胸犬上,造成急性心肌缺血,以左室排血时间(LVET)、排血前时间(PEP)、等容收缩时间(ICT).PEP/LVET比值和ICT/LVET比值,观察心肌缺血时生脉液用药前后心脏功能的改变.结果表明,急性心肌缺血时LVET值变小,PEP、ICT、PEP/LVET和ICT/LVET值增大,给药后,该药可使心脏功能明显好转.
In 12 open-chest mongrel dogs under anesthesia acute myocardial ischemia was caused by a micrometer constrictor.The effect of Shengmaiye on the myocardial ischemia models was observed by measuring the left ventricular ejection time (LVET), pre-ejection period (PEP), isovolumic contraction time(ICT), PEP/LVET radio and ICT/LVET radio. The results showed that the PEP, ICP, PEP/LVET and ICT/LVET were significantly increased, the LVET was shortened in myocardial ischemia. In the treatedgroup after taking the drug,the heart function was significantly improved