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消化性溃疡患者血清LPO含量及SOD活性变化的初步研究 被引量:2

PRELIMINARY STUDY OF SERUM LIPID PEROXIDES CONTENT AND SUPEROXIDE DISMUTASE ACTIVITIES IN PATIENTS WITH PEPTIC ULCER
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摘要 对84例消化性溃疡患者血清LPO含量及Gu,Zn—SOD活性进行了测定。发现胃溃疡及复合性溃疡患者血清LPO含量明显高于正常对照(P<0.001),血清Cu,Zn—SOD活性明显低于正常对照(P<0.01);十二指肠球部溃疡患者血清LPO含量有升高趋势,而血清Gu,Zn-SOD活性在正常范围。结果提示:胃溃疡的发生可能与氧自由基的作用有关。 Serum lipid peroxides (LPO) contents and Cu, Zn-superoxide dismutase (Cu, Zn-SOD) were measured in 84 patients with peptic ulcer. The result showed that serum LPO content was stenificantly higher in patients with gastric ulcer and composite ulcet than normal subjects (P <0. 001), while serum Cu. Zn-SOD activities decreased markedly as compared with the mormal (P <0. 01 ). The serum LPO content of the patients with duodend ulcer was slightly higher than narmal subjects, but serum Cu, Zn-SOD activities remained normal. It suggested that oxygen free radicals may play a role in formation of gastric ulcer.
机构地区 黔南州人民医院
出处 《贵州医药》 CAS 1996年第6期323-324,共2页 Guizhou Medical Journal
关键词 消化性溃疡 脂质过氧化酶 超氧化物歧化酶 Peptic ulcer lipid peroxides Cu,Zn-Superoxide dismutase Oxygen free radicals
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  • 1Benjamin F. Dickens,Tong Mak,William B. Weglicki. Lysosomal lipolytic enzymes, lipid peroxidation, and injury[J] 1988,Molecular and Cellular Biochemistry(1-2):119~123

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