摘要
对84例消化性溃疡患者血清LPO含量及Gu,Zn—SOD活性进行了测定。发现胃溃疡及复合性溃疡患者血清LPO含量明显高于正常对照(P<0.001),血清Cu,Zn—SOD活性明显低于正常对照(P<0.01);十二指肠球部溃疡患者血清LPO含量有升高趋势,而血清Gu,Zn-SOD活性在正常范围。结果提示:胃溃疡的发生可能与氧自由基的作用有关。
Serum lipid peroxides (LPO) contents and Cu, Zn-superoxide dismutase (Cu, Zn-SOD) were measured in 84 patients with peptic ulcer. The result showed that serum LPO content was stenificantly higher in patients with gastric ulcer and composite ulcet than normal subjects (P <0. 001), while serum Cu. Zn-SOD activities decreased markedly as compared with the mormal (P <0. 01 ). The serum LPO content of the patients with duodend ulcer was slightly higher than narmal subjects, but serum Cu, Zn-SOD activities remained normal. It suggested that oxygen free radicals may play a role in formation of gastric ulcer.
出处
《贵州医药》
CAS
1996年第6期323-324,共2页
Guizhou Medical Journal
关键词
消化性溃疡
脂质过氧化酶
超氧化物歧化酶
Peptic ulcer lipid peroxides Cu,Zn-Superoxide dismutase Oxygen free radicals