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CD4^+CD25^(bright)调节性T细胞在皮肤病中的作用

Roles of CD4^+ CD25^(bright) Regulatory T cells in Skin Diseases
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摘要 CD4^+CD25^(bright)调节性T细胞是一个具有免疫抑制功能的T细胞亚群,丰要通过细胞间直接接触发挥抑制作用,参与机体自身免疫耐受的形成。近年研究发现,CD4^+cD25^(bright)出调节性T细胞在多种皮肤科相关疾病,如感染性疾病、自身免疫病、肿瘤、银屑病以及特应性皮炎的发生发展中起一定的作用。 CD4^＋CD25^bright regulatory T cells are a specific subset of T lymphocytes with the function of immune suppression through intercellular contact, and play a pivotal role in the development of self immunotolermace. Recently, it has been implicated that they have a critical function in the pathogenesis of various skin diseases, such as infectious diseases, autoimmune diseases, tumors, psoriasis and atopic dermatitis.
作者 赵建斌 龚匡隆 王千秋
机构地区 中国医学科学院 江苏省徐州市第一人民医院
出处 《国际皮肤性病学杂志》 2006年第4期254-256,共3页 International Journal of Dermatology and Venereology
关键词 调节性T细胞 皮肤疾病 T淋巴细胞 Regulatory T cells Skin diseases T-Lymphocytes
分类号 R751 [医药卫生—皮肤病学与性病学]
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参考文献20

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国际皮肤性病学杂志
2006年 第4期

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