摘要
目的:了解常州地区泌尿生殖道支原体对抗生素的耐药情况,为临床治疗提供参考依据。方法:使用珠海丽珠公司解脲脲原体和人型支原体分离鉴定、计数、药敏试剂盒进行检测。结果:600例求诊者中检出233例解脲脲原体(Uu)、25例解脲脲原体(Uu)和人型支原体(Mh)混合感染,总的感染率为43.0%。药敏结果显示,Uu对强力霉素、美满霉素、交沙霉素、克拉霉素、罗红霉素、阿奇霉素、氧氟沙星、左氧氟沙星、司帕沙星的耐药率分别为:2.1%、3.0%,9.9%、5.2%,52.8%、33.0%,33.5%、15.5%,31.3%;Uu和Mh混合感染对上述药物的耐药率分别为:8.0%,4.0%、16.0%,100.0%、100.0%,100.0%、64.0%,44.0%,60.0%。结论:泌尿生殖道感染主要是解脲脲原体(Uu),其次为人型支原体(Mh)。解脲脲原体(Uu)对强力霉素的耐药率最低,解脲脲原体(Uu)和人型支原体(Mh)混合感染对美满霉素的耐药率最低,对克拉霉素、罗红霉素、阿奇霉素有严重的耐药性。
Objective： To study the resistance of Ureaplasma urealyticum （Uu） and Mycoplasma hominis （Mh） in Changzhou area and reasonable administration of the drug. Methods： Mucoplasmaics kit of Lizhu company was used to diagnose Uu and Mh （isolation, counting, susceptibility）. Results： In 600 patients, 233 cases were Uu positive, 25 cases were mixed infection. The total infection ratio was 43.0%. The antimicrobial susceptibility of Uu to doxycycline, minocycline, josamycin, clarithromycin, roxithromycin, azithromycin, ofloxacin, levofloxacin, and spafloxacin was 2.1%, 3.0%, 9.9%, 5.2%, 52.8%, 33.0%, 33.5%, 15.5%, 31.3% respectively; and the antimicrobial susceptibility of Uu and Mh mixed infection was 8.0%, 4.0%, 16.0%, 100.0%, 100.0%, 100.0%, 64.0%, 44.0%, 60.0% respectively. Conclusion： In urinogenital mycoplasma infection, the positive rate of Uu is higher than that of Mh. Doxycycline shows the lowest susceptibility for Uu and minocy cline shows the lowest susceptibility for Uu＋Mh. The highest susceptibility of clarithromycin, roxithromycin, azihromycin for Uu＋ Mh.
出处
《现代预防医学》
CAS
北大核心
2006年第7期1112-1114,共3页
Modern Preventive Medicine
关键词
解脲脲原体
人型支原体
耐药性
Ureaplasma urealyticum （Uu）
Mycoplasma hominis （Mh）
susceptibility
