摘要
目的观察严重创伤和手术创伤病人早期输注冷沉淀的临床效果。方法对58例ISS90评分平均为(29.86)分的严重创伤以及手术创伤病人输注冷沉淀共1073单位(平均18.5单位);随机对25例病人输注冷沉淀前、后进行血常规、出血时间及纤维结合蛋白含量测定;并对其中19例严重创伤患者在输注冷沉淀前后0.5、2、24小时测定血浆纤维结合蛋白水平。结果患者输注冷沉淀后与输注前相比,出血时间明显缩短;血浆纤维结合蛋白水平在输注后0.5小时显著提高,2小时后仍然维持在较高水平。结论对严重创伤和手术创伤患者早期输注冷沉淀可提高患者血浆纤维结合蛋白水平,缩短出血时间,加快创伤组织修复。
Objective To explore the clinical effect of early cryoprecipitate transfusion in patients with severe trauma and operative trauma. Methods 1073 units （average 18.5 units） of cryoprecipitate were transfused into 58 cases of severe trauma and operative trauma patients whose average injury severity score （ISS90） was 29.86. The blood routine , bleeding time and fibronectin （Fn） of 25 cases were determined before and after cryoprecipitate transfusion; the plasma Fn level of 19 severe trauma patients were determined after cryoprecipitate transfusion at 0.5 hour and 24 hours. Results The bleeding time shorted significantly after cryoprecipitate transfusion;the plasma Fn level significantly increased after cryoprecipitate transfusion at 0.5 hour and sti severe trauma and operativll kept at a high level at 2 hours. Conclusion Early cryoprecipitatetransfusion fore trauma patients can increase the plasma Fn level of patients , short the bleeding time and accelerate the repair of traumatic tissues.
出处
《国际医药卫生导报》
2006年第12期45-47,共3页
International Medicine and Health Guidance News
关键词
冷沉淀
严重创伤
手术
修复
Cryoprecipitate Severe trauma Operation Repair
