摘要
体外培养SW872细胞,油酸诱导其分化为成熟的脂肪细胞,然后加入重组人白细胞介素6 (IL-6)观察其对SW872成熟脂肪细胞促酰化蛋白(ASP)分泌的影响。结果显示0.6mmol/L油酸刺激72 h能成功诱导SW872前脂肪细胞分化为成熟的脂肪细胞；IL-6对SW872成熟脂肪细胞ASP的分泌具有明显的抑制作用,且表现为时间和剂量依赖效应。
SW872 cells were cultured in vitro with oleic acid and differentiated into mature adipocytes. The role of interleukin-6 （IL-6） in the secretion of acylation-stimulating protein （ASP） in mature SW872 adipocytes was observed. The results suggested that IL-6 significantly inhibited ASP secretion into the media in a dose- and time-dependent manner in mature SW872 adipocytes .
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2006年第3期279-280,共2页
Chinese Journal of Endocrinology and Metabolism
基金
国家自然科学基金(No.30170442)
国家自然科学基金国际合作交流项目(No.30311120163)
