摘要
目的探讨24 h食管持续pH监测对诊断胃食管反流的临床意义。方法用自制佩带式24 h食管pH监测系统,对82有例胃食管反流症状的患者和40例无上消化道症状的正常人进行了常态下24 h食管pH监测。结果国人24h食管pH监测指标的正常阈值:食管pH<4次数<22.11;pH<4总时间的%<1.89;站立位pH<4时间%<2.42;卧位pH<4时间%<1.0;pH<4大于5 min以上次数0次;综合指标总计分<15。24 h食管持续pH监测各项参数GERD组明显高于正常组差别显著(P<0.01)。结论 24 h食管pH监测对诊断GER有重要意义,综合指标总计分的高低与反流症状轻重有关,是判断生理性和病理性反流的重要指标。
AIMS To study the value of 24-hour pH monitoring of esophagus in the diagnosis of gastroesophagus reflux diseases (GERD). METHODS 24-hour pH of esophagus was measured with home-made ambulatory esophageal pH monitor in 82 GERD patients and 40 normal subjects. RESULTS In normal subjects: number of pH<4:<22.11 ( +2s); total time(%) pH<4:<1.89; upright(%):<2.42;supine(%):<1.0; number of reflux episodes>5 min, pH<4: 0; total refluent score(TRS)<15. The refluent score was significantly higher in patients with GERD than that in normal subjects (P<0.01). CONCLUSIONS 24-hour pH monitoring of the esophagus is valuable in the diagnosis of GERD. TRS is an important parameter to distinguish normal and pathologic gastroesophages reflux.
