摘要
采用幽门结扎法诱发大鼠胃溃疡模型，观察外源性ＳＯＤ对大鼠实验性胃溃疡的保护作用。结果表明：ＳＯＤ保护组大鼠胃粘膜丙二醛含量明显低于溃疡组（Ｐ＜０．０５）；胃粘膜损伤指数：ＳＯＤ组为１７．５±０．５，溃疡组为８１．５±１１．６。提示ＳＯＤ可对抗胃溃疡形成过程中的脂质过氧化损伤作用。
Using the rat model of gastric ulcer,we observed the effect of SOD on gastric ulcer of rats.The results indicated that SOD significantly decreased the content of malondialdehyde (MDA) in gastric muscosa,and decreased the injury index.It is suggested that SOD may scavenge the oxygen free radical formed in the process of gastric ulcer,and have the protective effect on gastric mucosal.
出处
《济宁医学院学报》
1996年第3期18-20,共3页
Journal of Jining Medical University
关键词
胃溃疡
超氧化物歧化酶
大鼠
Superoxide dismutase
Gastric ulcer
Malondiadehyde
