摘要
本文从立体化学和反应机理方面综述了Corey化学酶的催化作用及其在有机不对称合成中的应用,指出了Corey化学酶与酶的相同点和不同点,对于关键的反应过程态均以空间关系更为清楚的构象式表示。
This review examines the catalysis and application of Corey' s chemzyme in asymmetric organic synthesis from the viewpoint of stereochemistry and reaction mechanism. The similarities and differences between chemzyme and enzyme are shown clearly in the paper. In order to give more clear the spacial relationship some key transient states are described by the comformational formula.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
1996年第5期403-414,共12页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金
关键词
化学酶
不对称合成
醇胺
邻二胺
催化作用
chemzyme, asymmetric synthesis, hydroxy amine, vicinal diamine
