摘要
介绍了４类具有络合性质或潜在的络合性质的４－取代苄基－２，６－哌嗪二酮化合物的合法。所合成的化合物中有些表现出明显的体外抑制白血细胞Ｐ３８８生长的活性。
The development of several methods for the synthesis of four classes of 1,4-disubstituted piperazine-2,6-diones which have chelating effects or latent chelating effects is described. Some of them are proved to be considerably effective against P388 cells in vitro.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1996年第8期1235-1239,共5页
Chemical Journal of Chinese Universities
关键词
哌嗪二酮
合成
抗肿瘤
Piperazine-2,6-dione, Synthesis,Anticancer
