摘要
目的探讨微量营养素与维生素D(VitD)缺乏性佝偻病的相关性。方法选择佝偻病患儿312例和健康儿童297例,采用原子吸收光谱法测定血钙、镁及锌、铁、铜、铅和铬水平。结果佝偻病患儿血钙、锌、铁水平降低,而铅、镁升高,组间差异具有非常著性意义(P均<0.01);相关性分析,佝偻病与钙、锌、铁呈负相关;与血铅、镁呈正相关(P均<0.01)。佝偻病血微量营养素间相关性分析,钙与锌、铁,锌与铁呈正相关,铅与钙、锌、铁,镁与铁呈明显负相关。佝偻病铅中毒发生率为8.01%。结论血钙、锌、铁降低及铅、镁升高与佝偻病密切相关。补充锌、铁制剂及高铅干预治疗是佝偻病防治的措施之一。
Objective To investigate the relationship between trace elements and raehitis in children. Methods Three hundred and twelve patients with rachitis and 297 healthy children were selected for this study. Blood zinc（Zn）, iron（Fe） ,plasma copper（Cu） ,calcium （Ca） ,magnesium（Mg）,lead（Pb） and cadmium（Cd） were assayed by atomic absorption spectrophotometer. Results The levels of Zn, Fe, Cu of rachitis in blood were significantly lower than those of healthy children, while the levels of Mg, Pb were higher. There were significant differences between 2 groups（ P〈 0.01 ）. Correlation analysis showed that there was a negative correlation between rachitis and the levels of Ca, Zn and Fe; but the positive correlation between rachitis and the levels of Mg, Pb （P〈 0.01 ）. On correlational analysis of trace elements in blood, there were positive correlation between Ca and Zn, Fe, Zn and Fe. While there was negative correlation between Pb and Ca, Zn, Fe, Mg and Fe. The incidence of lead poison was 8.01% in children with rachitis. Conclusions The decrease of Ca, Zn, Fe and the increase of Mg,Pb were related to rachitis. The supplement of Zn, Fe and the interference of lead poison will be important in prevention and treatment of rachitis in children.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2006年第11期703-704,共2页
Journal of Applied Clinical Pediatrics
基金
青岛市科技发展指导计划项目资助[(2004)Kzd-42]
