摘要
目的探讨通过弥散张量白质纤维束成像(DTI)指导脑肿瘤微创神经外科手术的效果和应用前景。方法对52例脑恶性肿瘤患者进行扫描,根据融合图像,对其中的34例患者行了导航下微创肿瘤切除术,对18例进行常规微创开颅脑肿瘤切除术。分析了手术效果、并发症及随访资料。结果二次手术率为0,肿瘤全切除率为86·5%(45/52)。病残率为11·5%(6/52)。1例(1·9%)死亡。结论应用弥散张量白质纤维束成像指导恶性脑肿瘤手术能使神经外科微创手术从皮层保护发展到核团保护、神经束保护。结合神经导航和开放MRI,将推动微创神经外科手术的发展。
Objective To investigate the effects and prospect of application of diffusion tensor imaging （DTI） tractography in minimally invasive surgery of brain tumors. Methods DTI tractography was performed in 52 patients with malignant brain tumors. Based on the DTI tractography results, 34 of the 52 patients underwent operation under neuro-navigation, and 18 of the 52 patients underwent operation routine minimally invasive craniotomy and tumor resection without neuro-navigation. Results The rate of total tumor resection was 86.5% （45/52）. The mortality was 1.9% （1/52）. The disability rate was 11.5% （6/52）. No case needed the second operation. Conclusion DTI tractography has raised the minimally invasive neurosurgery to the level of protecting the nuclei and nerve tracts and guiding intra-operative management of infiltration of deep-seated tumors, especially when combined with neuro-navigation and interventional MRI.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2006年第19期1301-1304,共4页
National Medical Journal of China
