摘要
乌珠穆沁羊的椎骨数量变异是由于同源框基因Ｈｏｍｅｏｂｏｘ的一些对位点突变。占乌珠穆沁羊２０％的１４个胸椎个体和４０％的７个腰椎的个体都属于多椎骨羊，以及３％的１４个胸惟７个腰椎的多推骨羊等，都是Ｈｏｍｅｏｂｏｘ不同对位点的隐性突变纯合子、多胸椎和多腰椎基因的基因频率分别为０．４５和０．６３．基因型频率分别为０．２０４７和０．３９６７。在正常胸椎数（Ｔ１３）和正常腰椎数（Ｌ６）的羊中，杂合子频率明显高于纯合子频率。多脊椎是乌珠穆沁羊的重要遗传特征。
The mutatants of Homeobox genes in Mongolian sheep were confirmedby counting the vertebrate numbers of the cervical,thoratic,lumbar zones.The normalvertebral column of the sheep was seven cervical,thirteen thoratic,six lumbar and foursacral vertebrae (C7:Tl3:L6:S4).About 20%of Mongolian sheep showed T14 and40%L7 in the axial skeleton. These sheep were all homozygous,but the phenotypesshowed incomplete penetrance(97.1%).The gene frequences of T14 and L7 were 0.45and 0.63 respectively.The homeobox genes related to T14 and L7 were Hoxa-5,Hoxa-6,Hoxa-11,hoxc-8,Hoxd-4,Hoxd-9and Hoxd-11
基金
国家自然科学基金
