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含G-CSF的预激方案治疗难治复发性及老年性急性髓系白血病的临床观察 被引量:2

Clinical investigation of G-CSF priming regimen in treatment of relapsing,refractory and senile acute myeloid leukemia
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摘要 目的评估预激方案治疗难治复发性及老年性急性髓系白血病的临床疗效.方法予粒细胞集落刺激因子[惠尔血(G-CSF)100 μg/m^2,12小时一次,第1~14天,皮下注射];阿糖胞苷[(Ara-C)10 mg/m^2,12小时一次,皮下注射,第1~14天];联合阿克拉霉素(ACR) 5~7 mg/(m^2·d),静滴,第1~8天或10~14 mg/(m^2·d),静滴,第1~4天]或高三尖杉酯碱[(HHT) 1 mg/(m^2·d),静滴,第1~14天]联合治疗复发、难治及老年性AML 16例.结果 16例中CR 9例(56.3%),PR 2例(12.5%),NR 5例(31.3%),总有效率68.8%.本组>70岁老年患者4例中,CR 3例,NR 1例(为MDS继发AML后难治),总CR率75.0%.所有患者均完成疗程,无1例发生治疗相关性死亡.结论该方案对难治复发、继发性及老年性AML疗效较好且不良反应少.
出处 《实用肿瘤杂志》 CAS 2006年第3期249-250,共2页 Journal of Practical Oncology
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参考文献4

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二级参考文献3

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