期刊文献+

改良型鼻咽腔内加温装置的可行性研究

Effectiveness of Improved Intracavity Microwave Thermotherapy for Nasopharyngeal Carcinoma
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摘要 优化设计出与鼻咽腔解剖结构相适宜,并具有最佳热场分布的鼻咽癌热疗辐射器和定位器,通过基础实验,定性观察其定位及热场分布;探讨临床应用的安全性和有效性。在体模实验中,经过短时间、高功率加热之后,热变色液晶薄膜显示热场分布为包罗定位器的半月形状。5个测温点分别测出了辐射器旁、辐射器所在的鼻咽腔侧壁、顶壁、对侧壁以及底壁的温度分布:有辐射器的软管处最热;有辐射器的定位器外侧壁及顶壁次之,但温度差异不大,均可达到有效治疗温度;无辐射器的软管一侧,即对侧壁温度明显下降;定位器底部即鼻咽腔底壁的温度最低,软腭可避免过热。动物实验结果同样证实了鼻咽辐射器配置固定器后各部位的温度分布,并且动物实验中的温度数据均较体模实验的低,分析可能是由于动物实验中存在血液循环带走了部分热量造成的,但它不影响定性地分析两个实验结果的一致性。 This study sought to evaluate the safety and effectiveness of intracavity microwave thermotherapy for nasopharyngeal carcinoma(NPC). The temperature images of the heating range were attained immediately after heating by LCP. The aim temperature (equal or over 40℃) was achieved and then uniform thermal distribution in these areas was seen. Either phantoms or animal tests suggest that the temperature of all detected points are ranged from top to low: para-radiator,ipsilateral,parietal and contralateral wall of the simulated nasopharygeal cavity. Intracavity microwave thermotherapy is effective and safe for NPC by either phantoms or animal tests.
出处 《生物医学工程学杂志》 EI CAS CSCD 北大核心 2006年第3期657-659,共3页 Journal of Biomedical Engineering
关键词 鼻咽癌 腔内加温 幅射器 热场分布 Nasopharyngeal carcinoma Intracavity thermotherapy Applicator Thermal distribution
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参考文献7

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