摘要
目的评价非全身肝素化状态下冠状动脉造影(CAG)的安全性。方法 100例择期冠状动脉脉造影的病人随机分为常规肝素抗凝组50例(肝素组)和无肝素抗凝组50例(非肝素组),非肝素组要求从鞘管进入股动脉到CAG结束在10min内完成。观察CAG期间及其后6h内病人发生卒中、新发生的外周动脉血栓、穿刺及非穿刺部位出血并发症情况。结果肝素组术中及术后无卒中、新发生的外周动脉血栓和非穿刺部位出血发生,穿刺部位血肿4例(8.0%);非肝素组术后1例(2.0%)发生短暂性脑缺血发作,无新发生的外周动脉血栓、穿刺和非穿刺部位出血发生。结论对技术熟练的术者,在10min内,非全身肝素化状态下完成从鞘管进入股动脉到CAG操作是安全的,可减少穿刺和非穿刺部位出血并发症的发生。
Objective To evaluate the safety of coronary angiography(CAG) without heparinization. Methods One hundred patients who would accept elective CAG were divided into two groups named heparin group ( CAG with heparinization) and beparin-free group (CAG without heparinization) at random. The precedures were required to be finished within 10 minutes for heparin-free group. Stroke, new thrombus in peripheral artery, the complications of hemorrhage at the artery puncture site and non-puncture site were observed from the time of insetting the sheath into the artery to 6 hours after CAG. Results There were no srtoke, new thrombus in peripheral artery and hemorrhage at the non-puncture site and four patients (8.0%) had the complication of haematoma at the artery puncture sites in heparin group. There were no stroke, new thrombus in peripheral artery and hemorrhage at the artery puncture site and non-puncture site and one patient (2.0%) suffered from transient cerebral ischemia attack in the heparin-free group. Conclusions If the experienced operators can finish the procedures from insetting the sheath into the artery to the end of CAG within 10 minutes, the procedures of CAG without heparinization are safe. CAG without heparinization can decrease the complication of hemorrhage at the artery puncture site and non-puncture site.
出处
《中华老年多器官疾病杂志》
2006年第1期30-32,共3页
Chinese Journal of Multiple Organ Diseases in the Elderly
关键词
血管造影
经腔
经皮冠状动脉
肝素
angiography, transluminal, percutaneous coronary
heparin