摘要
应用放射免疫法测定了125例儿童(年龄自2月至14岁)空腹血浆胃泌素(gastrin)和胃泌素释放肽(gastrin-releasing peptide,GRP)。胃泌素和GRP的均值和实测范围分别为14.0±14.9,0～98.0 pmol/L和8.8士8.2,0～48.0 pmol/L。两种激素的浓度无显著的性别差异。胃泌素以2月至3岁以下组的含量为最高,其均值为12～14岁组的4倍以上。结果表明,胃泌素的浓度与年龄呈负相关(r=-0.50,P<0.001),而GRP的浓度则与年龄无相关性(P>0.05)。本文讨论了在不同年龄组的儿童的空腹血浆浓度的变化。
Plasma gastrin and gastrin-releasing peptide (GRP) were measured by RIA in 125 fasted children, aged from 2 months to 14 years. The mean values and ranges of gastrin and GRP were 14. 0±14. 9,0-98. 0 pmol/L and 8. 8 ±8. 2,0 - 48. Opmol/L respectively. The plasma concentrations of gastrin and GRP showed no significant difference be-tween male and female. The mean value of gastrin concentration was highest in children younger than 3 years.being four times higher than the mean value in those aged from 12 to 14 years. Statistical analysis of these data revealed that the mean value of gastin decreased with advancing age(r= -0. 50.P<0. 001). But the mean value of GRP had no statictical correlation with age. The negative correlation of plasma gastrin concentration with age in fasred children was discussed.
出处
《上海医药》
CAS
北大核心
1996年第4期28-29,共2页
Shanghai Medical & Pharmaceutical Journal
关键词
儿童
血浆
胃泌素释放肽
gastrin
gastrin-releasing peptide(GRP):children
